Author: Ma Jun
Language: English
ISBN/ISSN: 9787040176759
Published on: 2006-01
Hardcover
This book offers a comprehensive look into the science of gene expression and regulation. Focusing on topics such as actions of nuclear receptors, RNA processing, and DNA methylation and imprinting, Gene Expression and Regulation is edited by a leading biologist and includes contributions by experts in the field.
● Written and compiles by world known experts, it reflects all the current issues in gene regulation, including gene transcriptor, transcription factors, activation mechanism of gene transcription, restraining mechanism, factors controlling the growth of the cell, the proteins determining the death of the cells, small RNA functions, genome alalysis, DNA supercoiling structures, research on the power of transcription factors, plant development, gene therapy and HIV, etc;
● There are altogether 35 chapters, with each chapter summing up the latest research results in one specific field. The content compiled into five parts: the history, gene transcriptor, adjusting factors, genome and special topics;
● It is suitable for postgraduates of life sciences and specialized researchers and undergraduates in relevant fields;
● Written in English and printed in color.
About the Editor
Preface
Section Ⅰ The History
Chapter 01 Transcription: The Never Ending Story
Section Ⅱ The Machinery
Chapter 02 The General Transcription Machinery and Preinitiation Complex Formation
Chapter 03 The Dynamic Association of RNA Polymerase II with Initiation. Elongation, and RNA Processing Factors during the Transcription Cycle
Chapter 04 General Cofactors: TFIID, Mediator and USA
Chapter 05 Chromatin and Regulation of Gene Expression
Chapter 06 HATs and HDACs 111
Chapter 07 Structure and Function of Core Promoter Elements in RNA Polymerase II Transcription
Section Ⅲ The Regulators
Chapter 08 Transcriptional Activators and Activation Mechanisms
Chapter 09 Transcriptional Repressors and Repression Mechanisms
Chapter 10 STATs in Cytokine-mediated Transcriptional Regulation
Chapter 11 Transcriptional Regulation by Smads
Chapter 12 The Rb and E2F Families of Proteins
Chapter 13 c-Jun: A Complex Tale of a Simple Transcription Factor
Chapter 14 HIV Tat and the Control of Transcriptional Elongation
Chapter 15 Post-translational Modifications of the p53 Transcription Factor
Chapter 16 Actions of Nuclear Receptors
Chapter 17 NFAT and MEF2, Two Families of Calcium-dependent Transcription Regulators
Chapter 18 Hox Genes
Chapter 19 Nuclear Factor-kappa B
Chapter 20 The ATF Transcription Factors in Cellular Adaptive Responses
Section Ⅳ The Genome
Chapter 21 Function and Mechanism of Chromatin Boundaries
Chapter 22 Heterochromatin and X Inactivation
Chapter 23 DNA Methylation Regulates Genomic Imprinting, X Inactivation, and Gene Expression during Mammalian Development
Chapter 24 Comparative Genomics of Tissue Specific Gene Expression
Chapter 25 Transcription and Genomic Integrity
Chapter 26 Cell Death and Transcription
Section Ⅴ Special Topics
Chapter 27 Pre-mRNA Splicing in Eukaryotic Cells
Chapter 28 Genome Organization: The Effects of Transcription-driven DNA Supercoiling on Gene Expression Regulation
Chapter 29 The Biogenesis and Function of MicroRNAs
Chapter 30 Transcription Factor Dynamics
Chapter 31 Actin, Actin-Related Proteins and Actin-Binding Proteins in Transcriptional Control
Chapter 32 Wnt Signaling and Transcriptional Regulation
Chapter 33 Regulatory Mechanisms for Floral Organ Identity Specification inArabidopsis thaliana
Chapter 34 Transcription Control in Bacteria
Chapter 35 Gene Therapy: Back to the Basics
Language: English
ISBN/ISSN: 9787040176759
Published on: 2006-01
Hardcover
This book offers a comprehensive look into the science of gene expression and regulation. Focusing on topics such as actions of nuclear receptors, RNA processing, and DNA methylation and imprinting, Gene Expression and Regulation is edited by a leading biologist and includes contributions by experts in the field.
● Written and compiles by world known experts, it reflects all the current issues in gene regulation, including gene transcriptor, transcription factors, activation mechanism of gene transcription, restraining mechanism, factors controlling the growth of the cell, the proteins determining the death of the cells, small RNA functions, genome alalysis, DNA supercoiling structures, research on the power of transcription factors, plant development, gene therapy and HIV, etc;
● There are altogether 35 chapters, with each chapter summing up the latest research results in one specific field. The content compiled into five parts: the history, gene transcriptor, adjusting factors, genome and special topics;
● It is suitable for postgraduates of life sciences and specialized researchers and undergraduates in relevant fields;
● Written in English and printed in color.
About the Editor
Preface
Section Ⅰ The History
Chapter 01 Transcription: The Never Ending Story
Section Ⅱ The Machinery
Chapter 02 The General Transcription Machinery and Preinitiation Complex Formation
Chapter 03 The Dynamic Association of RNA Polymerase II with Initiation. Elongation, and RNA Processing Factors during the Transcription Cycle
Chapter 04 General Cofactors: TFIID, Mediator and USA
Chapter 05 Chromatin and Regulation of Gene Expression
Chapter 06 HATs and HDACs 111
Chapter 07 Structure and Function of Core Promoter Elements in RNA Polymerase II Transcription
Section Ⅲ The Regulators
Chapter 08 Transcriptional Activators and Activation Mechanisms
Chapter 09 Transcriptional Repressors and Repression Mechanisms
Chapter 10 STATs in Cytokine-mediated Transcriptional Regulation
Chapter 11 Transcriptional Regulation by Smads
Chapter 12 The Rb and E2F Families of Proteins
Chapter 13 c-Jun: A Complex Tale of a Simple Transcription Factor
Chapter 14 HIV Tat and the Control of Transcriptional Elongation
Chapter 15 Post-translational Modifications of the p53 Transcription Factor
Chapter 16 Actions of Nuclear Receptors
Chapter 17 NFAT and MEF2, Two Families of Calcium-dependent Transcription Regulators
Chapter 18 Hox Genes
Chapter 19 Nuclear Factor-kappa B
Chapter 20 The ATF Transcription Factors in Cellular Adaptive Responses
Section Ⅳ The Genome
Chapter 21 Function and Mechanism of Chromatin Boundaries
Chapter 22 Heterochromatin and X Inactivation
Chapter 23 DNA Methylation Regulates Genomic Imprinting, X Inactivation, and Gene Expression during Mammalian Development
Chapter 24 Comparative Genomics of Tissue Specific Gene Expression
Chapter 25 Transcription and Genomic Integrity
Chapter 26 Cell Death and Transcription
Section Ⅴ Special Topics
Chapter 27 Pre-mRNA Splicing in Eukaryotic Cells
Chapter 28 Genome Organization: The Effects of Transcription-driven DNA Supercoiling on Gene Expression Regulation
Chapter 29 The Biogenesis and Function of MicroRNAs
Chapter 30 Transcription Factor Dynamics
Chapter 31 Actin, Actin-Related Proteins and Actin-Binding Proteins in Transcriptional Control
Chapter 32 Wnt Signaling and Transcriptional Regulation
Chapter 33 Regulatory Mechanisms for Floral Organ Identity Specification inArabidopsis thaliana
Chapter 34 Transcription Control in Bacteria
Chapter 35 Gene Therapy: Back to the Basics